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KMID : 0380619890210060884
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Korean Journal of Food Science and Technology
1989 Volume.21 No. 6 p.884 ~ p.889
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Effects of Evening Primrose Oil on Plasma Cholesterol and Fatty Acid Compositions of Erythrocyte Membrane and Aorta in Rats
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Abstract
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Weanling male Sprague-Dawleyrats were divided into 4 groups according to the level of plasma cholesterol and then fed diets containing 15%(w/w) corn oil, lard or evening primrose oil (EPO) with 0.5% (w/w) of cholesterol. Corn oil without cholesterol was used as a die;,ary lipid source of control diet. After 4 weeks of feeding, the fatty acid compositions of the red blood cell membrane and aorta phospholipids were analyzed together with the plasma cholesterol level. The rats fed with EPO characterized by its content of gamma-linolenic acid (GLA) showed lower cholesterol concentration in plasma than the other groups. In the corn oil groups, plasma cholesterol level was not affected by the addition of dietary cholesterol. The concentrations of dihomogamma-linolenic acid and arachidonic acid, metabolites of GLA, in the tissue were increased in the EPO group compared with the other groups.
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